Serotonin, an important brain neurotransmitter, is key in the regulation of appetite, mood, and melatonin production. The presence of serotonin in the brain is associated with a balanced emotional state. This is achieved in part by decreasing the activity of certain excitatory hormones, including dopamine and noradrenaline. Serotonin also acts as a satiety signal in the brain, thereby naturally regulating food intake. Additionally, as a precursor of melatonin, serotonin is involved in regulating sleep patterns.
5-HTP is derived naturally from the seeds of the Griffonia plant, unlike tryptophan which is produced synthetically or through bacterial fermentation. 5-HTP crosses into the brain more readily than tryptophan as it is able to cross the blood-brain barrier without competition for uptake. 5-HTP is significantly more effective than tryptophan. In clinical practice, it has been commonly accepted that 50 mg of 5-HTP is roughly equivalent to 500 mg of tryptophan. Finally, research studies have shown 5-HTP to be safe at levels as high as 900 mg. As a result, 5-HTP is a safe and effective brain serotonin levels.
